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INFORMATICASI
2008
57views more  INFORMATICASI 2008»
13 years 4 months ago
Analysis of an Immune Algorithm for Protein Structure Prediction
Andrew J. Bennett, Roy L. Johnston, Eleanor Turpin...
BMCBI
2010
116views more  BMCBI 2010»
13 years 4 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2011
12 years 8 months ago
Determinants of Antigenicity and Specificity in immune response for Protein Sequences
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
Yulong Wang, Wenjun Wu, Nicolas N. Negre, Kevin P....
APBC
2004
123views Bioinformatics» more  APBC 2004»
13 years 6 months ago
Empirical Knowledge and Genetic Algorithms for Selection of Amide I Frequencies in Protein Secondary Structure Prediction
Here we investigate an extension of a previously suggested "automatic amide I frequency selection procedure" where we introduce an additional criterion utilizing empiric...
Joachim A. Hering, Peter R. Innocent, Parvez I. Ha...
BMCBI
2010
98views more  BMCBI 2010»
13 years 4 months ago
Prediction of protein structural classes for low-homology sequences based on predicted secondary structure
Background: Prediction of protein structural classes (a, b, a + b and a/b) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulat...
Jian-Yi Yang, Zhen-Ling Peng, Xin Chen