Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
Yulong Wang, Wenjun Wu, Nicolas N. Negre, Kevin P....
Here we investigate an extension of a previously suggested "automatic amide I frequency selection procedure" where we introduce an additional criterion utilizing empiric...
Joachim A. Hering, Peter R. Innocent, Parvez I. Ha...
Background: Prediction of protein structural classes (a, b, a + b and a/b) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulat...