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BMCBI
2005
201views more  BMCBI 2005»
13 years 5 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
RECOMB
2006
Springer
14 years 5 months ago
Efficient Enumeration of Phylogenetically Informative Substrings
We study the problem of enumerating substrings that are common amongst genomes that share evolutionary descent. For example, one might want to enumerate all identical (therefore co...
Stanislav Angelov, Boulos Harb, Sampath Kannan, Sa...
TCBB
2008
126views more  TCBB 2008»
13 years 5 months ago
Combinatorial Approaches for Mass Spectra Recalibration
Mass spectrometry has become one of the most popular analysis techniques in Proteomics and Systems Biology. With the creation of larger data sets, the automated recalibration of ma...
Sebastian Böcker, Veli Mäkinen
GECCO
2011
Springer
232views Optimization» more  GECCO 2011»
12 years 8 months ago
Mutation rates of the (1+1)-EA on pseudo-boolean functions of bounded epistasis
When the epistasis of the fitness function is bounded by a constant, we show that the expected fitness of an offspring of the (1+1)-EA can be efficiently computed for any point...
Andrew M. Sutton, Darrell Whitley, Adele E. Howe
GECCO
2007
Springer
162views Optimization» more  GECCO 2007»
13 years 11 months ago
Using pair approximations to predict takeover dynamics in spatially structured populations
The topological properties of a network directly impact the flow of information through a system. For example, in natural populations, the network of inter-individual contacts aff...
Joshua L. Payne, Margaret J. Eppstein