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BMCBI
2008
117views more  BMCBI 2008»
13 years 6 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
13 years 11 months ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
13 years 11 months ago
Highly Scalable and Accurate Seeds for Subsequence Alignment
We propose a method for finding seeds for the local alignment of two nucleotide sequences. Our method uses randomized algorithms to find approximate seeds. We present a dynamic ...
Abhijit Pol, Tamer Kahveci
KDD
2010
ACM
252views Data Mining» more  KDD 2010»
13 years 10 months ago
Fast query execution for retrieval models based on path-constrained random walks
Many recommendation and retrieval tasks can be represented as proximity queries on a labeled directed graph, with typed nodes representing documents, terms, and metadata, and labe...
Ni Lao, William W. Cohen
BMCBI
2006
131views more  BMCBI 2006»
13 years 6 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...