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» Artificial Chemistries and Metabolic Pathways
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BMCBI
2006
135views more  BMCBI 2006»
13 years 6 months ago
Correcting ligands, metabolites, and pathways
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
Martin A. Ott, Gert Vriend
JELIA
2004
Springer
13 years 11 months ago
Towards a Logical Analysis of Biochemical Pathways
Biochemical pathways or networks are generic representations used to model many different types of complex functional and physical interactions in biological systems. Models based ...
Patrick Doherty, Steve Kertes, Martin Magnusson, A...
BMCBI
2011
13 years 1 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
EVOW
2009
Springer
13 years 4 months ago
Evolutionary Approaches for Strain Optimization Using Dynamic Models under a Metabolic Engineering Perspective
One of the purposes of Systems Biology is the quantitative modeling of biochemical networks. In this effort, the use of dynamical mathematical models provides for powerful tools in...
Pedro Evangelista, Isabel Rocha, Eugénio C....
BMCBI
2011
12 years 10 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...