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» Automatic generation of gene finders for eukaryotic species
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BMCBI
2007
96views more  BMCBI 2007»
13 years 5 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
BMCBI
2004
87views more  BMCBI 2004»
13 years 5 months ago
prot4EST: Translating Expressed Sequence Tags from neglected genomes
Background: The genomes of an increasing number of species are being investigated through generation of expressed sequence tags (ESTs). However, ESTs are prone to sequencing error...
James Wasmuth, Mark L. Blaxter
NAR
2008
119views more  NAR 2008»
13 years 5 months ago
TreeFam: 2008 Update
TreeFam (http://www.treefam.org) was developed to provide curated phylogenetic trees for all animal gene families, as well as orthologue and paralogue assignments. Release 4.0 of ...
Jue Ruan, Heng Li, Zhongzhong Chen, Avril Coghlan,...
BMCBI
2006
116views more  BMCBI 2006»
13 years 5 months ago
TaxMan: a taxonomic database manager
Background: Phylogenetic analysis of large, multiple-gene datasets, assembled from public sequence databases, is rapidly becoming a popular way to approach difficult phylogenetic ...
Martin Jones, Mark Blaxter
BMCBI
2006
137views more  BMCBI 2006»
13 years 5 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan