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VLDB
1999
ACM
224views Database» more  VLDB 1999»
13 years 10 months ago
Optimal Grid-Clustering: Towards Breaking the Curse of Dimensionality in High-Dimensional Clustering
Many applications require the clustering of large amounts of high-dimensional data. Most clustering algorithms, however, do not work e ectively and e ciently in highdimensional sp...
Alexander Hinneburg, Daniel A. Keim
BMCBI
2008
98views more  BMCBI 2008»
13 years 5 months ago
MTAP: The Motif Tool Assessment Platform
Background: In recent years, substantial effort has been applied to de novo regulatory motif discovery. At this time, more than 150 software tools exist to detect regulatory bindi...
Daniel Quest, Kathryn Dempsey, Mohammad Shafiullah...
BIBE
2003
IEEE
133views Bioinformatics» more  BIBE 2003»
13 years 11 months ago
A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...
BMCBI
2008
145views more  BMCBI 2008»
13 years 5 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2004
158views more  BMCBI 2004»
13 years 5 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...