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» Bayesian Protein Family Classifier
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ISMB
1993
13 years 6 months ago
Using Dirichlet Mixture Priors to Derive Hidden Markov Models for Protein Families
A Bayesian method for estimating the amino acid distributions in the states of a hidden Markov model (HMM) for a protein familyor the columns of a multiple alignment of that famil...
Michael Brown, Richard Hughey, Anders Krogh, I. Sa...
BMCBI
2010
104views more  BMCBI 2010»
13 years 5 months ago
Using simple artificial intelligence methods for predicting amyloidogenesis in antibodies
Background: All polypeptide backbones have the potential to form amyloid fibrils, which are associated with a number of degenerative disorders. However, the likelihood that amyloi...
Maria Pamela C. David, Gisela P. Concepcion, Eduar...
BMCBI
2007
119views more  BMCBI 2007»
13 years 5 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2011
12 years 9 months ago
Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure
Background: Protein secondary structure prediction provides insight into protein function and is a valuable preliminary step for predicting the 3D structure of a protein. Dynamic ...
Zafer Aydin, Ajit Singh, Jeff Bilmes, William Staf...