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» Bio-inspired reverse engineering of regulatory networks
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Publication
295views
12 years 3 months ago
The Age of Analog Networks.
A large class of systems of biological and technological relevance can be described as analog networks, that is, collections of dynamic devices interconnected by links of varying s...
Claudio Mattiussi, Daniel Marbach, Peter Dürr, Da...
BMCBI
2005
178views more  BMCBI 2005»
13 years 5 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BIOCOMP
2008
13 years 6 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...

Publication
195views
12 years 3 months ago
Analog Genetic Encoding for the Evolution of Circuits and Networks
This paper describes a new kind of genetic representation called analog genetic encoding (AGE). The representation is aimed at the evolutionary synthesis and reverse engineering of...
Claudio Mattiussi, Dario Floreano
JMLR
2012
11 years 7 months ago
Bayesian regularization of non-homogeneous dynamic Bayesian networks by globally coupling interaction parameters
To relax the homogeneity assumption of classical dynamic Bayesian networks (DBNs), various recent studies have combined DBNs with multiple changepoint processes. The underlying as...
Marco Grzegorczyk, Dirk Husmeier