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IJCBDD
2008
141views more  IJCBDD 2008»
13 years 5 months ago
CLUSS2: an alignment-independent algorithm for clustering protein families with multiple biological functions
: CLUSS is an algorithm proposed for clustering both alignable and non-alignable protein sequences. However, CLUSS tends to be ineffective on protein datasets that include a large ...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski
BIBE
2007
IEEE
147views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A New Alignment-Independent Algorithm for Clustering Protein Sequences
—The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important, the challenge is to identify subfamilies of evolut...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski
BMCBI
2006
166views more  BMCBI 2006»
13 years 5 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2004
96views more  BMCBI 2004»
13 years 4 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2005
108views more  BMCBI 2005»
13 years 4 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...