77 search results - page 1 / 16 » Cancer disease: integrative modelling approaches |
ISBI
2006
IEEE
14 years 5 months ago
2006
IEEE
Cancer is a complex disease in which a variety of phenomena interact over a wide range of spatial and temporal scales. In this article a theoretical framework will be introduced t...
BMCBI
2010
13 years 4 months ago
2010
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
BMCBI
2007
13 years 4 months ago
2007
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
IJCBDD
2011
12 years 11 months ago
2011
: This study presents a novel network methodology to identify prognostic gene signatures. Implication networks based on prediction logic are used to construct genome-wide coexpress...
BICOB
2010
Springer
13 years 5 months ago
2010
Springer
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...