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» Case study in modeling and simulation validation methodology
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BMCBI
2010
165views more  BMCBI 2010»
13 years 5 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
BMCBI
2006
99views more  BMCBI 2006»
13 years 5 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2005
93views more  BMCBI 2005»
13 years 5 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
BMCBI
2005
156views more  BMCBI 2005»
13 years 5 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer
SIAMAM
2000
100views more  SIAMAM 2000»
13 years 5 months ago
Phase Transition Near a Liquid-Gas Coexistence Equilibrium
Effects of small perturbations from a liquid-gas coexistence equilibrium (the Maxwell states) is studied for an isothermal (or isentropic) gas-liquid phase transition in a sealed o...
Xiao-Ping Wang, Xinfu Chen