524 search results - page 1 / 105 » Challenges of sequencing human genomes |
BIB
2010
13 years 2 months ago
2010
Massively parallel sequencing technologies continue to alter the study of human genetics. As the cost of sequencing declines, next-generation sequencing (NGS) instruments and data...
BMCBI
2006
13 years 5 months ago
2006
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
RECOMB
2008
Springer
14 years 5 months ago
2008
Springer
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
BMCBI
2005
13 years 5 months ago
2005
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
IMSCCS
2006
IEEE
13 years 11 months ago
2006
IEEE
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...