10 search results - page 2 / 2 » Chromosomal Breakpoint Detection in Human Cancer |
BMCBI
2010
13 years 5 months ago
2010
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
BMCBI
2010
13 years 5 months ago
2010
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
ISBRA
2009
Springer
13 years 11 months ago
2009
Springer
Abstract. DNA copy number is the number of replicates of a contiguous segment of DNA on the genome. Copy number alteration (CNA) is a genetic abnormality in which the number of the...
NAR
2010
12 years 11 months ago
2010
Chromosome translocations and gene fusions are frequent events in the human genome and have been found to cause diverse types of tumor. ChimerDB is a knowledgebase of fusion genes...
BMCBI
2011
12 years 8 months ago
2011
Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal pop...