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ICCABS
2011
12 years 8 months ago
CloG: A pipeline for closing gaps in a draft assembly using short reads
— Closing of gaps in draft assemblies using Next Generation Sequencing (NGS) data is becoming increasingly important. In this paper we present CloG, a software pipeline that uses...
Xing Yang, Daniel Medvin, Giri Narasimhan, Deborah...
BIBM
2010
IEEE
286views Bioinformatics» more  BIBM 2010»
13 years 2 months ago
Evaluation of short read metagenomic assembly
Advances in sequencing technologies have equipped researchers with the ability to sequence the collective genome of entire microbial communities commonly referred to as metagenomi...
Anveshi Charuvaka, Huzefa Rangwala
BMCBI
2010
154views more  BMCBI 2010»
13 years 5 months ago
An algorithm for automated closure during assembly
Background: Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can invol...
Sergey Koren, Jason R. Miller, Brian Walenz, Grang...
BMCBI
2010
148views more  BMCBI 2010»
13 years 5 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...