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» Clustering the annotation space of proteins
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BMCBI
2005
97views more  BMCBI 2005»
13 years 4 months ago
Clustering the annotation space of proteins
Background: Current protein clustering methods rely on either sequence or functional similarities between proteins, thereby limiting inferences to one of these areas. Results: Her...
Victor Kunin, Christos A. Ouzounis
BMCBI
2004
125views more  BMCBI 2004»
13 years 4 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
NAR
2010
148views more  NAR 2010»
12 years 11 months ago
SIMAP - a comprehensive database of pre-calculated protein sequence similarities, domains, annotations and clusters
The prediction of protein function as well as the reconstruction of evolutionary genesis employing sequence comparison at large is still the most powerful tool in sequence analysi...
Thomas Rattei, Patrick Tischler, Stefan Götz,...
JCB
2007
83views more  JCB 2007»
13 years 4 months ago
Evolutionary Networks in the Formatted Protein Sequence Space
In our recent work, a new approach to establish sequence relatedness, by walking through the protein sequence space, was introduced. The sequence space is built from 20 amino acid...
Zakharia M. Frenkel, Edward N. Trifonov
NAR
2007
136views more  NAR 2007»
13 years 4 months ago
DBAli tools: mining the protein structure space
The DBAli tools use a comprehensive set of structural alignments in the DBAli database to leverage the structural information deposited in the Protein Data Bank (PDB). These tools...
Marc A. Martí-Renom, Ursula Pieper, Mallur ...