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» Combinatorial method of splice sites prediction
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RECOMB
2010
Springer
13 years 7 months ago
Leveraging Sequence Classification by Taxonomy-Based Multitask Learning
In this work we consider an inference task that biologists are very good at: deciphering biological processes by bringing together knowledge that has been obtained by experiments u...
Christian Widmer, Jose Leiva, Yasemin Altun, Gunna...
ICDM
2009
IEEE
152views Data Mining» more  ICDM 2009»
13 years 12 months ago
SLIDER: Mining Correlated Motifs in Protein-Protein Interaction Networks
Correlated motif mining (CMM) is the problem to find overrepresented pairs of patterns, called motif pairs, in interacting protein sequences. Algorithmic solutions for CMM thereb...
Peter Boyen, Frank Neven, Dries Van Dyck, Aalt-Jan...
RECOMB
2008
Springer
14 years 5 months ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
BMCBI
2010
118views more  BMCBI 2010»
13 years 5 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...