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CSB
2004
IEEE
158views Bioinformatics» more  CSB 2004»
13 years 8 months ago
Algorithms for Association Study Design Using a Generalized Model of Haplotype Conservation
There is considerable interest in computational methods to assist in the use of genetic polymorphism data for locating disease-related genes. Haplotypes, contiguous sets of correl...
Russell Schwartz
BMCBI
2006
135views more  BMCBI 2006»
13 years 4 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
BMCBI
2006
109views more  BMCBI 2006»
13 years 4 months ago
HaploRec: efficient and accurate large-scale reconstruction of haplotypes
Background: Haplotypes extracted from human DNA can be used for gene mapping and other analysis of genetic patterns within and across populations. A fundamental problem is, howeve...
Lauri Eronen, Floris Geerts, Hannu Toivonen
BMCBI
2010
176views more  BMCBI 2010»
13 years 2 months ago
Haplotype association analyses in resources of mixed structure using Monte Carlo testing
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
Ryan Abo, Jathine Wong, Alun Thomas, Nicola J. Cam...
BMCBI
2008
151views more  BMCBI 2008»
13 years 4 months ago
Application of the Linux cluster for exhaustive window haplotype analysis using the FBAT and Unphased programs
Background: Genetic association studies have been used to map disease-causing genes. A newly introduced statistical method, called exhaustive haplotype association study, analyzes...
Hiroyuki Mishima, Andrew C. Lidral, Jun Ni