13 search results - page 1 / 3 » Comparative mapping of sequence-based and structure-based pr... |
BMCBI
2005
13 years 5 months ago
2005
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
BMCBI
2008
13 years 5 months ago
2008
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
RECOMB
1999
Springer
13 years 10 months ago
1999
Springer
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
BMCBI
2010
13 years 5 months ago
2010
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
CIBCB
2006
IEEE
13 years 12 months ago
2006
IEEE
The vast number of expressed sequence tags (ESTs) in public databases provides an important resource for comparative and functional genomics. A variety of methods based on homology...