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RECOMB
2006
Springer
14 years 5 months ago
Detecting MicroRNA Targets by Linking Sequence, MicroRNA and Gene Expression Data
MicroRNAs (miRNAs) have recently been discovered as an important class of non-coding RNA genes that play a major role in regulating gene expression, providing a means to control th...
Jim C. Huang, Quaid Morris, Brendan J. Frey
NAR
2006
142views more  NAR 2006»
13 years 5 months ago
miRNAMap: genomic maps of microRNA genes and their target genes in mammalian genomes
Recent work has demonstrated that microRNAs (miRNAs) are involved in critical biological processes by suppressing the translation of coding genes. This work develops an integrated...
Paul Wei-Che Hsu, Hsien-Da Huang, Sheng-Da Hsu, Li...
JCB
2007
130views more  JCB 2007»
13 years 5 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2010
176views more  BMCBI 2010»
13 years 5 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...