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» Comparing Sequences with Segment Rearrangements
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FSTTCS
2003
Springer
13 years 10 months ago
Comparing Sequences with Segment Rearrangements
Computational genomics involves comparing sequences based on “similarity” for detecting evolutionary and functional relationships. Until very recently, available portions of th...
Funda Ergün, S. Muthukrishnan, Süleyman ...
RECOMB
2005
Springer
14 years 5 months ago
Stability of Rearrangement Measures in the Comparison of Genome Sequences
We present data-analytic and statistical tools for studying rates of rearrangement of whole genomes and to assess the stability of these methods with changes in the level of resol...
David Sankoff, Matthew Mazowita
SDM
2007
SIAM
109views Data Mining» more  SDM 2007»
13 years 6 months ago
Segmentations with Rearrangements
Sequence segmentation is a central problem in the analysis of sequential and time-series data. In this paper we introduce and we study a novel variation to the segmentation proble...
Aristides Gionis, Evimaria Terzi
RECOMB
2004
Springer
14 years 5 months ago
Chromosomal breakpoint re-use in the inference of genome sequence rearrangement
In order to apply gene-order rearrangement algorithms to the comparison of genome sequences, Pevzner and Tesler [9] bypass gene finding and ortholog identification, and use the or...
David Sankoff, Phil Trinh
BMCBI
2008
135views more  BMCBI 2008»
13 years 5 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...