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CIBCB
2009
IEEE
13 years 6 months ago
Improved prediction of trans-membrane spans in proteins using an artificial neural network
Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...
Julia Koehler, Ralf Mueller, Jens Meiler
BMCBI
2006
112views more  BMCBI 2006»
13 years 5 months ago
Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
Pantelis G. Bagos, Theodore D. Liakopoulos, Stavro...
CIBCB
2007
IEEE
13 years 11 months ago
A Comparison of Sequence Kernels for Localization Prediction of Transmembrane Proteins
Abstract— We applied Support Vector Machines to the prediction of the subcellular localization of transmembrane proteins, and compared the performance of different sequence kerne...
Stefan Maetschke, Marcus Gallagher, Mikael Bod&eac...
BMCBI
2008
95views more  BMCBI 2008»
13 years 5 months ago
Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
Alinda Nagy, Hédi Hegyi, Krisztina Farkas, ...
BMCBI
2008
95views more  BMCBI 2008»
13 years 5 months ago
PURE: A webserver for the prediction of domains in unassigned regions in proteins
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...