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» Complex networks as control paradigm for complex systems
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BMCBI
2006
152views more  BMCBI 2006»
13 years 5 months ago
A two-stage approach for improved prediction of residue contact maps
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
Alessandro Vullo, Ian Walsh, Gianluca Pollastri
BMCBI
2006
129views more  BMCBI 2006»
13 years 5 months ago
A literature-based similarity metric for biological processes
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
BMCBI
2006
133views more  BMCBI 2006»
13 years 5 months ago
Web-based analysis of the mouse transcriptome using Genevestigator
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...
CORR
2006
Springer
90views Education» more  CORR 2006»
13 years 5 months ago
On entropy for mixtures of discrete and continuous variables
Let X be a discrete random variable with support S and f : S S be a bijection. Then it is wellknown that the entropy of X is the same as the entropy of f(X). This entropy preserva...
Chandra Nair, Balaji Prabhakar, Devavrat Shah
BMCBI
2007
148views more  BMCBI 2007»
13 years 5 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...