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ISAAC
2005
Springer
81views Algorithms» more  ISAAC 2005»
13 years 10 months ago
Complexity and Approximation of the Minimum Recombination Haplotype Configuration Problem
We study the complexity and approximation of the problem of reconstructing haplotypes from genotypes on pedigrees under the Mendelian Law of Inheritance and the minimum recombinant...
Lan Liu, Xi Chen, Jing Xiao, Tao Jiang
WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
13 years 3 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick
WABI
2010
Springer
178views Bioinformatics» more  WABI 2010»
13 years 3 months ago
Haplotype Inference on Pedigrees with Recombinations and Mutations
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
Yuri Pirola, Paola Bonizzoni, Tao Jiang