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» Computational Approaches to Drug Design
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GECCO
2006
Springer
191views Optimization» more  GECCO 2006»
13 years 9 months ago
Automating the drug scheduling with different toxicity clearance in cancer chemotherapy via evolutionary computation
The toxicity of an anticancer drug is cleared from the body by different processes, including saturable metabolic and nonsaturable renal-excretion pathways. According to the princ...
Yong Liang, Kwong-Sak Leung, Tony Shu Kam Mok
RECOMB
2010
Springer
13 years 7 months ago
An Algorithmic Framework for Predicting Side-Effects of Drugs
Abstract. One of the critical stages in drug development is the identification of potential side effects for promising drug leads. Large scale clinical experiments aimed at discove...
Nir Atias, Roded Sharan
EDBT
2012
ACM
257views Database» more  EDBT 2012»
11 years 7 months ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh
GECCO
2004
Springer
13 years 10 months ago
Computer-Aided Peptide Evolution for Virtual Drug Design
Ignasi Belda, Xavier Llorà, Marc Martinell,...
CCE
2008
13 years 5 months ago
Optimal periodic control of a drug delivery system
Administration of certain drugs at a steady rate results in deterioration of drug effect, also known as drug tolerance. Periodic delivery is an attractive option for minimizing to...
Subbarao Varigonda, Tryphon T. Georgiou, Ronald A....