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BMCBI
2006
192views more  BMCBI 2006»
13 years 5 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
RECOMB
2008
Springer
14 years 5 months ago
Accurate Computation of Likelihoods in the Coalescent with Recombination Via Parsimony
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of app...
Jotun Hein, Rune B. Lyngsø, Yun S. Song
BMCBI
2007
132views more  BMCBI 2007»
13 years 5 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen
CEC
2010
IEEE
13 years 6 months ago
A novel memetic algorithm for constrained optimization
In this paper, we present a memetic algorithm with novel local optimizer hybridization strategy for constrained optimization. The developed MA consists of multiple cycles. In each ...
Jianyong Sun, Jonathan M. Garibaldi