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BMCBI
2006
138views more  BMCBI 2006»
13 years 5 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
APBC
2004
13 years 6 months ago
Mega Weaver: A Simple Iterative Approach for BAC Consensus Assembly
Hierarchical genome assembly can be divided into three distinct stages: sequencing and assembling shotgun reads for each of a series of selected BAC clones; assembling the resulti...
Daolong Wang, Mario Lauria, Bo Yuan, Fred A. Wrigh...
BMCBI
2007
130views more  BMCBI 2007»
13 years 5 months ago
Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data
Background: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) pr...
James J. Chen, Huey-miin Hsueh, Robert R. Delongch...
BMCBI
2008
104views more  BMCBI 2008»
13 years 5 months ago
Missing value imputation improves clustering and interpretation of gene expression microarray data
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
Johannes Tuikkala, Laura Elo, Olli Nevalainen, Ter...
BMCBI
2005
144views more  BMCBI 2005»
13 years 4 months ago
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...