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BMCBI
2010
115views more  BMCBI 2010»
13 years 4 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
NAR
2011
195views Computer Vision» more  NAR 2011»
12 years 7 months ago
MitoGenesisDB: an expression data mining tool to explore spatio-temporal dynamics of mitochondrial biogenesis
Mitochondria constitute complex and flexible cellular entities, which play crucial roles in normal and pathological cell conditions. The database MitoGenesisDB focuses on the dyna...
Jean-Christophe Gelly, Mickael Orgeur, Claude Jacq...
KDD
2002
ACM
183views Data Mining» more  KDD 2002»
14 years 5 months ago
E-CAST: A Data Mining Algorithm for Gene Expression Data
Data clustering methods have been proven to be a successful data mining technique in the analysis of gene expression data. The Cluster affinity search technique (CAST) developed b...
Abdelghani Bellaachia, David Portnoy, Yidong Chen,...
NN
2007
Springer
267views Neural Networks» more  NN 2007»
13 years 4 months ago
Modeling of gene regulatory networks with hybrid differential evolution and particle swarm optimization
In the last decade, recurrent neural networks (RNNs) have attracted more efforts in inferring genetic regulatory networks (GRNs), using time series gene expression data from micro...
Rui Xu, Ganesh K. Venayagamoorthy, Donald C. Wunsc...
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 4 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...