17 search results - page 2 / 4 » Context-dependent transcriptional regulations between signal... |
BMCBI
2006
13 years 5 months ago
2006
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
BMCBI
2010
13 years 5 months ago
2010
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
BMCBI
2006
13 years 5 months ago
2006
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
BMCBI
2005
13 years 4 months ago
2005
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
RECOMB
2003
Springer
14 years 5 months ago
2003
Springer
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...