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» Current approaches to gene regulatory network modelling
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BIOSYSTEMS
2007
111views more  BIOSYSTEMS 2007»
13 years 6 months ago
A Markovian approach to the control of genetic regulatory networks
This paper presents an approach for controlling gene networks based on a Markov chain model, where the state of a gene network is represented as a probability distribution, while ...
Peter C. Y. Chen, Jeremy W. Chen
CEC
2005
IEEE
13 years 12 months ago
Clustering-based approach to identify solutions for the inference of regulatory networks
Abstract- In this paper we address the problem of finding valid solutions for the problem of inferring gene regulatory networks. Different approaches to directly infer the depende...
Christian Spieth, Felix Streichert, Nora Speer, An...
CMSB
2006
Springer
13 years 10 months ago
Incorporating Time Delays into the Logical Analysis of Gene Regulatory Networks
Based on the logical description of gene regulatory networks developed by R. Thomas, we introduce an enhanced modelling approach that uses timed automata. It yields a refined quali...
Heike Siebert, Alexander Bockmayr
EMO
2005
Springer
108views Optimization» more  EMO 2005»
13 years 12 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
BMCBI
2007
186views more  BMCBI 2007»
13 years 6 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao