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» Decomposing Gene Expression into Cellular Processes
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PSB
2003
13 years 6 months ago
Decomposing Gene Expression into Cellular Processes
We propose a probabilistic model for cellular processes, and an algorithm for discovering them from gene expression data. A process is associated with a set of genes that particip...
Eran Segal, Alexis Battle, Daphne Koller
PSB
2004
13 years 6 months ago
Modeling Cellular Processes with Variational Bayesian Cooperative Vector Quantizer
Gene expression of a cell is controlled by sophisticated cellular processes. The capability of inferring the states of these cellular processes would provide insight into the mech...
Xinghua Lu, Milos Hauskrecht, Roger S. Day
RECOMB
2000
Springer
13 years 8 months ago
Tissue classification with gene expression profiles
Constantly improving gene expression profiling technologies are expected to provide understanding and insight into cancer related cellular processes. Gene expression data is also
Amir Ben-Dor, Laurakay Bruhn, Nir Friedman, Iftach...
BMCBI
2005
140views more  BMCBI 2005»
13 years 4 months ago
Dissecting systems-wide data using mixture models: application to identify affected cellular processes
Background: Functional analysis of data from genome-scale experiments, such as microarrays, requires an extensive selection of differentially expressed genes. Under many condition...
J. Peter Svensson, Renée X. de Menezes, Ing...
ICASSP
2011
IEEE
12 years 8 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero