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BMCBI
2007
233views more  BMCBI 2007»
13 years 5 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
IPPS
2006
IEEE
13 years 11 months ago
FPGA based architecture for DNA sequence comparison and database search
DNA sequence comparison is a computationally intensive problem, known widely since the competition for human DNA decryption. Database search for DNA sequence comparison is of grea...
Euripides Sotiriades, Christos Kozanitis, Apostolo...
BMCBI
2008
211views more  BMCBI 2008»
13 years 5 months ago
CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Svetlin Manavski, Giorgio Valle
FCCM
2006
IEEE
137views VLSI» more  FCCM 2006»
13 years 11 months ago
Single Pass, BLAST-Like, Approximate String Matching on FPGAs
Abstract: Approximate string matching is fundamental to bioinformatics, and has been the subject of numerous FPGA acceleration studies. We address issues with respect to FPGA imple...
Martin C. Herbordt, Josh Model, Yongfeng Gu, Bhara...
RIVF
2008
13 years 6 months ago
Speeding up subset seed algorithm for intensive protein sequence comparison
Abstract--Sequence similarity search is a common and repeated task in molecular biology. The rapid growth of genomic databases leads to the need of speeding up the treatment of thi...
Van Hoa Nguyen, Dominique Lavenier