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BMCBI
2007
108views more  BMCBI 2007»
13 years 5 months ago
Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants
Background: Single nucleotide polymorphisms (SNPs) and genes that exhibit presence/absence variation have provided informative marker sets for bacterial and viral genotyping. Iden...
Erin P. Price, John Inman-Bamber, Venugopal Thiruv...
BMCBI
2008
73views more  BMCBI 2008»
13 years 5 months ago
Parallel and serial computing tools for testing single-locus and epistatic SNP effects of quantitative traits in genome-wide ass
Background: Genome-wide association studies (GWAS) using single nucleotide polymorphism (SNP) markers provide opportunities to detect epistatic SNPs associated with quantitative t...
Li Ma, H. Birali Runesha, Daniel Dvorkin, John R. ...
CIBCB
2008
IEEE
13 years 11 months ago
Very large scale ReliefF for genome-wide association analysis
— The genetic causes of many monogenic diseases have already been discovered. However, most common diseases are actually the result of complex nonlinear interactions between mult...
Margaret J. Eppstein, Paul Haake
BMCBI
2011
12 years 9 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm
Background: Polymerase chain reaction with confronting two-pair primers (PCR-CTPP) method produces allelespecific DNA bands of different lengths by adding four designed primers an...
Cheng-Hong Yang, Yu-Huei Cheng, Li-Yeh Chuang, Hsu...