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» Detecting overlapping coding sequences in virus genomes
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BMCBI
2006
68views more  BMCBI 2006»
13 years 4 months ago
Detecting overlapping coding sequences in virus genomes
Background: Detecting new coding sequences (CDSs) in viral genomes can be difficult for several reasons. The typically compact genomes often contain a number of overlapping coding...
Andrew E. Firth, Chris M. Brown
BMCBI
2010
128views more  BMCBI 2010»
13 years 4 months ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro
DNA
2005
Springer
13 years 10 months ago
Two Proteins for the Price of One: The Design of Maximally Compressed Coding Sequences
Abstract. The emerging field of synthetic biology moves beyond conventional genetic manipulation to construct novel life forms which do not originate in nature. We explore the pro...
Bei Wang, Dimitris Papamichail, Steffen Mueller, S...
BMCBI
2005
125views more  BMCBI 2005»
13 years 4 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...
BMCBI
2008
113views more  BMCBI 2008»
13 years 4 months ago
Investigating selection on viruses: a statistical alignment approach
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...