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IJBRA
2010
134views more  IJBRA 2010»
13 years 3 months ago
Deterministic graph-theoretic algorithm for detecting modules in biological interaction networks
—Accumulating evidence suggests that biological systems exhibit modular organization. Accurate identification of modularity is vital for understanding this organization. A recen...
Roger L. Chang, Feng Luo, Stuart Johnson, Richard ...
ALMOB
2006
109views more  ALMOB 2006»
13 years 4 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2010
142views more  BMCBI 2010»
13 years 4 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
CANDC
2006
ACM
13 years 4 months ago
Identification of functional modules in a PPI network by clique percolation clustering
Large-scale experiments and data integration have provided the opportunity to systematically analyze and comprehensively understand the topology of biological networks and biochem...
Shi-Hua Zhang, Xue-Mei Ning, Xiang-Sun Zhang
BMCBI
2008
123views more  BMCBI 2008»
13 years 4 months ago
Functional module detection by functional flow pattern mining in protein interaction networks
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Young-Rae Cho, Lei Shi, Aidong Zhang