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BMCBI
2005
106views more  BMCBI 2005»
13 years 5 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2007
102views more  BMCBI 2007»
13 years 5 months ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
13 years 10 months ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....
BIB
2008
88views more  BIB 2008»
13 years 5 months ago
MEGA: A biologist-centric software for evolutionary analysis of DNA and protein sequences
The Molecular Evolutionary Genetics Analysis (MEGA) software is a desktop application designed for comparative analysis of homologous gene sequences either from multigene families...
Sudhir Kumar, Masatoshi Nei, Joel Dudley, Koichiro...
RECOMB
2004
Springer
14 years 6 months ago
Chromosomal breakpoint re-use in the inference of genome sequence rearrangement
In order to apply gene-order rearrangement algorithms to the comparison of genome sequences, Pevzner and Tesler [9] bypass gene finding and ortholog identification, and use the or...
David Sankoff, Phil Trinh