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BIOINFORMATICS
2005
151views more  BIOINFORMATICS 2005»
13 years 4 months ago
Differential and trajectory methods for time course gene expression data
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...
Yulan Liang, Bamidele Tayo, Xueya Cai, Arpad Kelem...
BMCBI
2011
12 years 8 months ago
A Simple Approach to Ranking Differentially Expressed Gene Expression Time Courses through Gaussian Process Regression
Background: The analysis of gene expression from time series underpins many biological studies. Two basic forms of analysis recur for data of this type: removing inactive (quiet) ...
Alfredo A. Kalaitzis, Neil D. Lawrence
BMCBI
2007
154views more  BMCBI 2007»
13 years 4 months ago
h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data
Background: An ever increasing number of techniques are being used to find genes with similar profiles from microarray studies. Visualization of gene expression profiles can aid t...
Yvonne E. Pittelkow, Susan R. Wilson
IJON
2008
128views more  IJON 2008»
13 years 4 months ago
Independent arrays or independent time courses for gene expression time series data analysis
In this paper we apply three different independent component analysis (ICA) methods, including spatial ICA (sICA), temporal ICA (tICA), and spatiotemporal ICA (stICA), to gene exp...
Sookjeong Kim, Jong Kyoung Kim, Seungjin Choi
RECOMB
2009
Springer
14 years 5 months ago
A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microarray Time Series
Abstract. Understanding the regulatory mechanisms that are responsible for an organism's response to environmental changes is an important question in molecular biology. A fir...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...