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CSB
2005
IEEE
126views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Discover True Association Rates in Multi-protein Complex Proteomics Data Sets
Experimental processes to collect and process proteomics data are increasingly complex, while the computational methods to assess the quality and significance of these data remain...
Changyu Shen, Lang Li, Jake Yue Chen
BMCBI
2007
166views more  BMCBI 2007»
13 years 4 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2007
215views more  BMCBI 2007»
13 years 4 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
GPEM
2007
119views more  GPEM 2007»
13 years 4 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...