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RECOMB
2006
Springer
14 years 6 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
IDEAL
2004
Springer
13 years 11 months ago
Prediction of Implicit Protein-Protein Interaction by Optimal Associative Feature Mining
Proteins are known to perform a biological function by interacting with other proteins or compounds. Since protein–protein interaction is intrinsic to most cellular processes, pr...
Jae-Hong Eom, Jeong Ho Chang, Byoung-Tak Zhang
NIPS
2004
13 years 7 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
BMCBI
2007
151views more  BMCBI 2007»
13 years 6 months ago
Identification of hot regions in protein-protein interactions by sequential pattern mining
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
Chen-Ming Hsu, Chien-Yu Chen, Baw-Jhiune Liu, Chih...
BMCBI
2006
166views more  BMCBI 2006»
13 years 6 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...