The strength of GIS is in providing a rich data infrastructure for combining disparate data in meaningful ways by using a spatial arrangement (e.g., proximity). As a toolbox, a GI...
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
It is of high biomedical interest to identify gene interactions and networks that are associated with developmental and physiological functions in the mouse embryo. There are now v...
Liangxiu Han, Jano I. van Hemert, Richard A. Baldo...
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...