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JMLR
2010
136views more  JMLR 2010»
13 years 24 days ago
Predicting the functions of proteins in Protein-Protein Interaction networks from global information
In this work we present a novel approach to predict the function of proteins in protein-protein interaction (PPI) networks. We classify existing approaches into inductive and tran...
Hossein Rahmani, Hendrik Blockeel, Andreas Bender
IJDMB
2007
114views more  IJDMB 2007»
13 years 5 months ago
A parallel edge-betweenness clustering tool for Protein-Protein Interaction networks
: The increasing availability of protein-protein interaction graphs (PPI) requires new efficient tools capable of extracting valuable biological knowledge from these networks. Amon...
Qiaofeng Yang, Stefano Lonardi
BMCBI
2005
169views more  BMCBI 2005»
13 years 5 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
13 years 11 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...
BMCBI
2010
124views more  BMCBI 2010»
13 years 6 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...