5 search results - page 1 / 1 » Discovering causal signaling pathways through gene-expressio... |
NAR
2010
12 years 11 months ago
2010
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
BMCBI
2005
13 years 4 months ago
2005
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
BICOB
2010
Springer
13 years 5 months ago
2010
Springer
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
BMCBI
2010
13 years 5 months ago
2010
Background: Co-evolution is the process in which two (or more) sets of orthologs exhibit a similar or correlative pattern of evolution. Co-evolution is a powerful way to learn abo...
BMCBI
2006
13 years 5 months ago
2006
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...