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» Dynamic simulation of regulatory networks using SQUAD
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JCB
2006
114views more  JCB 2006»
13 years 5 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
BMCBI
2010
164views more  BMCBI 2010»
13 years 5 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...
CEC
2007
IEEE
13 years 9 months ago
Emergence of feedback in artificial gene regulatory networks
In this paper, we present a model for simulating the evolution of development together with a method for the analysis of emergence of negative feedback inside the regulatory networ...
Till Steiner, Lisa Schramm, Yaochu Jin, Bernhard S...
HYBRID
2001
Springer
13 years 9 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
BMCBI
2005
189views more  BMCBI 2005»
13 years 5 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen