Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
Yao-Ting Huang, Kui Zhang, Ting Chen, Kun-Mao Chao
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
One of the main topics of research in genomics is determining the relevance of mutations, described in haplotype data, as causes of some genetic diseases. However, due to technolo...