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» Efficient Computation of Minimum Recombination with genotype...
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WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
13 years 4 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick
BMCBI
2005
67views more  BMCBI 2005»
13 years 6 months ago
Selecting additional tag SNPs for tolerating missing data in genotyping
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
Yao-Ting Huang, Kui Zhang, Ting Chen, Kun-Mao Chao
WABI
2010
Springer
178views Bioinformatics» more  WABI 2010»
13 years 4 months ago
Haplotype Inference on Pedigrees with Recombinations and Mutations
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
Yuri Pirola, Paola Bonizzoni, Tao Jiang
AAAI
2006
13 years 7 months ago
Efficient Haplotype Inference with Boolean Satisfiability
One of the main topics of research in genomics is determining the relevance of mutations, described in haplotype data, as causes of some genetic diseases. However, due to technolo...
Inês Lynce, João Marques-Silva