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» Empirical Bayes analysis of single nucleotide polymorphisms
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JCB
2008
94views more  JCB 2008»
13 years 5 months ago
Prioritize and Select SNPs for Association Studies with Multi-Stage Designs
Large-scale whole genome association studies are increasingly common, due in large part to recent advances in genotyping technology. With this change in paradigm for genetic studi...
Jing Li
BMCBI
2005
67views more  BMCBI 2005»
13 years 5 months ago
Selecting additional tag SNPs for tolerating missing data in genotyping
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
Yao-Ting Huang, Kui Zhang, Ting Chen, Kun-Mao Chao
BMCBI
2011
13 years 23 days ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
BMCBI
2008
126views more  BMCBI 2008»
13 years 5 months ago
Methods for evaluating gene expression from Affymetrix microarray datasets
Background: Affymetrix high density oligonucleotide expression arrays are widely used across all fields of biological research for measuring genome-wide gene expression. An import...
Ning Jiang, Lindsey J. Leach, Xiaohua Hu, Elena Po...
SP
2006
IEEE
132views Security Privacy» more  SP 2006»
13 years 11 months ago
Towards Automatic Generation of Vulnerability-Based Signatures
In this paper we explore the problem of creating vulnerability signatures. A vulnerability signature matches all exploits of a given vulnerability, even polymorphic or metamorphic...
David Brumley, James Newsome, Dawn Xiaodong Song, ...