Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
One of the central problems in modern biology is to identify the complete set of interactions among the proteins in a cell. The structural interaction of proteins and their domains...
Background: Many crucial cellular operations such as metabolism, signalling, and regulations are based on protein-protein interactions. However, the lack of robust protein-protein...
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...