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BIOINFORMATICS
2012
11 years 7 months ago
Epigenetic priors for identifying active transcription factor binding sites
Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...
BMCBI
2008
128views more  BMCBI 2008»
13 years 4 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
BMCBI
2008
128views more  BMCBI 2008»
13 years 4 months ago
SIGffRid: A tool to search for sigma factor binding sites in bacterial genomes using comparative approach and biologically drive
Background: Many programs have been developed to identify transcription factor binding sites. However, most of them are not able to infer two-word motifs with variable spacer leng...
Fabrice Touzain, Sophie Schbath, Isabelle Debled-R...
RECOMB
2003
Springer
14 years 5 months ago
Phylogenetically and spatially conserved word pairs associated with gene expression changes in yeasts
Background: Transcriptional regulation in eukaryotes often involves multiple transcription factors binding to the same transcription control region, and to understand the regulato...
Derek Y. Chiang, Alan M. Moses, Manolis Kamvysseli...
RECOMB
2007
Springer
13 years 11 months ago
Nucleosome Occupancy Information Improves de novo Motif Discovery
A complete understanding of transcriptional regulatory processes in the cell requires identification of transcription factor binding sites on a genomewide scale. Unfortunately, th...
Leelavati Narlikar, Raluca Gordân, Alexander...