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» Estimate haplotype frequencies in pedigrees
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BMCBI
2008
68views more  BMCBI 2008»
13 years 5 months ago
NullHap - a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles
Background: Laboratory techniques used to determine haplotypes are often too expensive for large-scale studies and lack of phase information is commonly overcome using likelihood-...
Robert M. Nowak, Rafal Ploski
BIOINFORMATICS
2007
90views more  BIOINFORMATICS 2007»
13 years 5 months ago
HAPLOPOOL: improving haplotype frequency estimation through DNA pools and phylogenetic modeling
In the context of disease association studies, haplotype frequencies are usually estimated from genotype data. In order to reduce genotyping costs, one can estimate the haplotype ...
Bonnie Kirkpatrick, Carlos Santos Armendariz, Rich...
JCB
2006
140views more  JCB 2006»
13 years 5 months ago
HAPLOFREQ-Estimating Haplotype Frequencies Efficiently
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...
Eran Halperin, Elad Hazan
RECOMB
2004
Springer
14 years 5 months ago
Perfect phylogeny and haplotype assignment
This paper is concerned with the reconstruction of perfect phylogenies from binary character data with missing values, and related problems of inferring complete haplotypes from h...
Eran Halperin, Richard M. Karp