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» Evolutionary Perspectives on Protein Thermodynamics
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ICCS
2004
Springer
13 years 10 months ago
Evolutionary Perspectives on Protein Thermodynamics
While modern evolutionary theory has emphasized the role of neutral evolution, protein biochemistry and biophysics has interpreted the properties of proteins as largely resulting f...
Richard A. Goldstein
BMCBI
2006
137views more  BMCBI 2006»
13 years 4 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BIOSYSTEMS
2008
83views more  BIOSYSTEMS 2008»
13 years 4 months ago
Hydrophobic condensation and modular assembly model of protein folding
Despite several decades of intense study, protein folding problem remains elusive. In this paper, we review current knowledge and the prevailing thinking in the field, and summari...
Tian-Yow Tsong, Chin-Kun Hu, Ming-Chya Wu
COMPLEXITY
2007
116views more  COMPLEXITY 2007»
13 years 4 months ago
Life, information, entropy, and time: Vehicles for semantic inheritance
abstractions provides an additional supra-phenotypic vehicle for semantic inheritance, which supports the cultural heritages around which civilizations revolve. The following three...
Antony R. Crofts
NAR
2007
109views more  NAR 2007»
13 years 4 months ago
GeneTrees: a phylogenomics resource for prokaryotes
The GeneTrees phylogenomics system pursues comparative genomic analyses from the perspective of gene phylogenies for individual genes. The GeneTrees project has the goal of provid...
Yuying Tian, Allan W. Dickerman