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» Evolving Fractal Proteins
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BMCBI
2007
113views more  BMCBI 2007»
13 years 5 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
RECOMB
2005
Springer
14 years 6 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
INFOCOM
2008
IEEE
14 years 6 days ago
Complex Network Measurements: Estimating the Relevance of Observed Properties
Abstract—Complex networks, modeled as large graphs, received much attention during these last years. However, data on such networks is only available through intricate measuremen...
Matthieu Latapy, Clémence Magnien
SAC
2004
ACM
13 years 11 months ago
Combining analysis and synthesis in a model of a biological cell
for ideas, and then abstract away from these ideas to produce algorithmic processes that can create problem solutions in a bottom-up manner. We have previously described a top-dow...
Ken Webb, Tony White
ALMOB
2007
155views more  ALMOB 2007»
13 years 6 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen