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» Exon discovery by genomic sequence alignment
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BIOINFORMATICS
2002
71views more  BIOINFORMATICS 2002»
13 years 5 months ago
Exon discovery by genomic sequence alignment
Burkhard Morgenstern, Oliver Rinner, Saïd Abd...
ICCS
2005
Springer
13 years 10 months ago
SWAT: A New Spliced Alignment Tool Tailored for Handling More Sequencing Errors
Abstract. There are several computer programs that align mRNA with its genomic counterpart to determine exon boundaries. Though most of these programs perform such alignment effici...
Yifeng Li, Hesham H. Ali
BMCBI
2007
183views more  BMCBI 2007»
13 years 5 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
BMCBI
2006
111views more  BMCBI 2006»
13 years 5 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
CSB
2002
IEEE
121views Bioinformatics» more  CSB 2002»
13 years 10 months ago
Fast and Sensitive Algorithm for Aligning ESTs to Human Genome
There is a pressing need to align growing set of expressed sequence tags (ESTs) to newly sequenced human genome. The problem is, however, complicated by the exon/intron structure ...
Jun Ogasawara, Shinichi Morishita